In 2018, when skin microbiota was the personal care word of the year, and everyone seemed to be involved in this topic and related new discovers, we decided to investigate whether cosmetic preservatives, known and used for their antimicrobial efficacy, could have any impact on the microbial population inhabiting our skin.

Despite all difficulties and unknown factors that could be encountered when testing skin microbiota, it is necessary to approach it and try to give preliminary answers that can be used as a starting point for further studies. First, evaluating the pros and cons of involved methodologies as In-vivo and In-vitro tests and finally having a look at the current state of the art and knowledge on the topic, running bibliographic research on studies focusing on cosmetic preservatives and skin microbiota.

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